I've owned one for about 20 years in .357 magnum and have shot one doe with it. Accurate, the sight it comes with is a POS and shot uncorrectably high. I put an aperture sight off a .22 on it what has elevation click adjust which works real neat for swapping from light .38 to heavy magnum.
The one problem I've had is case separation. It seems to do this only with nickel brass and reloaded a couple of times. Nickel is brittle compared to brass. I stick with brass now, no nickel cases. It only does this with .357 loads, It's a royal pain to get that brass out when it does that and I've scratched the chamber a bit which ain't good. But, it still works. Just keep the nickeled cases out of it.
It's a pretty accurate gun, about 4 moa at 100 yards with cast 158 and a little better with a JHP 180 Hornady. That's plenty accurate to deer hunt with.
I handload, so I'd go with that .454. That sound's pretty wild. I bet it kicks in a Puma. My gun, I don't know that it breaks 6 lbs and it has the 20" barrel. With a hot .357 in it, it'll rock ya a little bit.