Nope, not on purpose.But, do you carry a SA revolver for self defense in public? By circumstance I have and a cap and ball .44 at that, but I don't make a habit of it. My 9s carry a few more rounds, if nothing else.
The Single Action revolver slipped into obsolescence as a primary self defense tool over 100 years ago. I've got plenty of more appropriate designed pistols to use in that role.
If it's that I had handy, I wouldn't feel under armed. Over 20 years of shooting and competing with the things gives me a certain level of comfort in my ability to run one under stress- but doesn't mean that I'm going to set out intentionally to use one in that role.