[/ Carlton Nether, Customer Service for Beretta USA, tells us keeping a pistol magazine loaded for an extended period doesn't cause magazine spring failure, however, failures to feed can result. He says, "The ammo will 'roll' in the magazine. If the mags are kept loaded and moved around a lot -- say on a cop's belt -- the rolling action can, over time, cause creases in the cases. These creases can cause malfunctions. Also the top bullet will roll against the magazine lips and creasing can occur there as well. Just check old ammo that's been bouncing around in a magazine for a long time.
We tell police officers if they keep loaded magazines, take a few seconds to "cycle" the ammo. Periodically unload the mag and reload it in a different sequence. This movement will allow the bullets to be in different parts of the magazine and help eliminate creasing.
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Above is from the link Steelheart posted. This is why LE agency training units want the ammo cycled every couple of weeks in your duty firearm. This I knew already-- however, until now, I was under the impression that keeping the mag spring compressed will result in reliability issues. (Me with my thick head took the word of an old timer in the Academy for all these years about this subject) Upon my own research and talking to officials from AZ DPS and the Maricopa county Sheriff's office, I realize keeping a mag loaded for an extended period of time will not affect its performance. (Unless it is a duty weapon---see above in blue) To this end I retract any former statements that I made about the weakening of mag springs due to constant compression.