My experience with the Fobus E2 so far has been a little mixed. Bear in mind, I've only had it for two days now, and haven't had a chance to REALLY put it to the test, also this the first paddle holster I've owned, and I'm relatively new to semi-autos. So, with all that in mind, your mileage may vary. I plan on doing far more tinkering, adjusting, and just trying to hold my mouth right before I can give you any more than a "First impression" kind of response.
I got the Roto model and have been experimenting with different angles and with cross-draw, etc. It's very comfortable, both as a cross and strong-side draw holster. I've worn it around the house with the firearm in it, just to get used to the weight and feel. I honestly stopped noticing it was even there after about 20 minutes, (and I'm rather slim, and there's not a lot of "natural padding" over my hip bone.)
The tension screw for me has been the biggest issue thus far. So far, the idea of adjustable tension for me has really been more of a situation of "On or Off"
The gun is either very easy to draw, but a little loose in the holster, (not really scared of dropping the gun. It's tight enough to stay put if I was running or jumping, but a good hard blow to my torso, and It would probably send my firearm flying.)
BUT if I tighten just a little bit, (and I mean, finger tightening. Not using a screwdriver) the gun refuses to draw smoothly, if at all.
The way the holster is designed, if you do a quick snap STRAIGHT back, the gun will come out, but any slight deviation from straight out, and you just stand there tugging on the grip. Once I actually went to draw and pulled the gun, holster and all, out of my waistband, (which I don't think would be handy in a self-defense situation, as I do not with to perform field testing on the efficacy of neutralizing assailants with uncontrollable laughter.)
So far, the best combination I have found for myself so far is a straight vertical kant , strong side, with slight tension on the firearm. That seems to work well, but really makes the extra few bucks I sprung for the Roto model to be wasted cash.
At this point, I think that it's a good holster. It's very versatile, and it fits the gun fantastically well. I just think I haven't yet found the right angle, tension and draw technique combination to really take the best advantage of it. I'll post more as I experiment.