I've always liked the .41. I think a hot handload in the .41 is about all anyone can ask, loaded in a strong revolver like a Ruger Blackhawk. However, I've settled on the time honored .45 Colt in my Blackhawk or my .357s. I have a 6.5" .357 Blackhawk that I've killed hogs and deer with. .357 is a good round.
I do hunt hogs quite often. When I do, my .45 Colt Blackhawk pushing a 300 grain XTP out of its 4 5/8" barrel to 1200 fps rides on my hip. I've had to blood trail hogs before, even been turned on by one once. A powerful handgun that you can maneuver in heavy brush is appreciated when that happens.