What kind of home environment are you in? Slugs penetrate like crazy, a big 1 oz piece of lead going between 1500 and 1800 fps. You have the opposite problem with the #8 birdshot. Having a choice, I think I'd use the #8 and let them get close. The alternative would be using the slugs and choosing your fields of fire very, very carefully.
When ammo starts coming back, you might want to get some BB sized shot or #4 shot, minimum. 00 buck is of course the gold standard, but penetration with this can be brutal too so be careful and plan things out before you find yourself in a self defense situation.